Developing headquarters economy is an important strategy of China’s opening economy at a higher level and an effective development model for promoting China’s regional industrial transformation and coordination development. Based on the relative researches about space choices and decision-making behaviors of corporate headquarters，as well as the existing theories about formation conditions and dynamic mechanism of headquarters economy，the paper analyze the demand preferences of headquarters economy from four aspects of spatial position，economic factors，agglomeration conditions and business environment，by applying Location theory. And then，according to demand preferences of headquarters economy in the new era，the paper put forward several requirements for ‘soft’ and ‘hard’ environment construction in the Central Business District，with considering the spatial structure evolution effected by the agglomeration of corporate headquarters and the development trend of global urban planning and construction.