Since blood transfusion began in eighteenth century，transfusion medicine has undergone several major changes. The most epoch-making contribution was the discovery of the first human blood group-ABO blood type system，which was confirmed the relationship with hemolytic transfusion reaction in 1900. Since then，various blood transfusion techniques have been produced and widely used in clinic. The transfusion medicine has become an important independent system based on the continuous popularization，innovation and improvement of blood transfusion technology. In July 25，2016，after the approval by National Standardization Committee，transfusion medicine has been formally added to secondary disciplines，and a series of third-level disciplines were set up. Transfusion medicine ushered in unprecedented opportunities and challenges. This article introduces the application and development of various technologies，future trend and prospect of transfusion medicine，starting with the current situation of clinical transfusion technology in China. This article provides reference for the majority of blood transfusion operators and promotes the rapid development of new transfusion technology. This article starts with the current status of clinical blood transfusion technology in China，and some conditions about their popularization，application and problems are presented，thus making the reference on the development trend of blood transfusion technology. As a result，it will provide potent theory guide and basis for the development of the future transfusion and transfusion medicine workers.