Jiangsu is the leading demonstration area of the national innovation-driven strategy， which has innate innovation gene and acquired innovation ability， but the transformation ability of realistic innovation is relatively weak. Due to the unique economic development pattern in the past few decades， Jiangsu has formed a culture of lack of positive development， courage to try and tolerance and pragmatism. In the new era， Jiangsu has ushered in the decisive stage of building a well-off society at a high level. If we want to make a breakthrough in the drive of innovation and enhance the ability of innovation transformation， we must attach importance to the cultivation of innovation culture under the new economic development model. To understand the necessity and urgency of cultivating innovation culture from the ideological level； The old curing thinking driven by science and technology to drive innovation is to promote the realistic transformation of scientific and technological innovation with the cultivation of culture and the creation of atmosphere； the tactical level invigorates the stock of talents， builds the benchmarking of innovative enterprises， builds creative and brand awareness， builds an innovative platform， shapes innovative people， and increases the publicity of innovation.